moh
Moh 3-11-2010
1-carpidopa is dopa decarboxylase inhibitor
2- rasagiline: selective MAO-B
3-selegiline & tranylcipromine : MAO inhibitors
4- atomoxetine is selective NE reuptake inhibitor
5-cortcal stimulants: amphetamines,coccaine and pemoline
6-MORPHINE: pupil const,resp dep. and constipation
\7- METHADONE : controlled sub and analgesic
8- pure opioid antagonist: naltrexone
9-opioid with high dependance ability: diacylmorphine
10- SE of isotretinoin: conjunctivitis, pseudomotor cerebri and fetal abnormalities.
11-parenteral solutions isotonic with human rbcs have osmolality: 300
12-pharmacy bulk packages : For preparation of sterile parenterals and no antimicrobial included
13-max vol for bacteriostatic water4injection: 30 ml
14-alzeheimer due to defect in cholinergic transmission
15-dobutamine: B agonist and only parenteral
16-daltaparin : Prevention of stroke or coaggulation (not dissolveing)
17-method of administration of heparin: Iv and sc
18-least sedative anxiolytic: Buspirone
19-fat sol vitamin : Phytonadione
20-antioxidant: Ascorbic acid
21-fosinopril : Ace
22-irbesartan: Not used in 2nd and third trimester & used 4 diabetic nephropathy
23- dry mouth caused by ipratropium and montelukast(singulair]
24-milrinone: Positive inotropic
25- alopecia treated by minoxidil and finasteride
26- ticlopidine inhibits blood coaggulation.
27- grape fruit interferes with felodipine
28- auranofin used in rheumatoid arthritis
29- sotalol in anti arrythmic effect siimilar to amiodarone.
30- budesonide: Available as inhalation powder and oral mucosa should be rinsed after use.
(i am not sure of 22, 23 and 30)
31- If ICS and bronchodilator, the bronchodilator used first.
32- Colestipol : bile acid sequestrant.
33- Simvastatin: HMGCOA Reductase inh. And pregnancy category X.
34-Rosuvastatin: C.I. in: Active liver disease and myopathy.
35- Short acting hypnotic : Melatonin (not sure)
36 – Clozapine S.E.: agranulocytosis.
37- Rule of progestin component in combination contraceptive pills:
thickening of cervical mucosa making endometrial lining irreceptive for
fertilized ovum.
38 – Tinea: TTT: terbinafine and nystatin.
39- Famotidine interferes with histamine receptors.
40- Betamethasone: most potent systemic cortisone.
41- hypothyroidism treated by : dihydrotachysterol.
42- acute gout treated by : naproxen.
43- b lactamase producing staph. Treated by bacampicillin(not sure).
44- Sulfonamides antagonized by : PABA.
45- chlorohexidine and benzalkonium are antiseptics.
46- permethrin: only used topically.
47- rizatriptan and methysergide for ttt of migraine.
the answer in APPLETON LANGE was both.
48- lactase enz used in : lactose intolerance.
49- endorphins: endogenous peptides.
50 disadv. Of cimetidine : inh of hepatic enzymes.
51-lactulose: laxative and decreases ammonia levels.
52-mesalamina(asacol®) used for IBD
53- aspirin inhibits clotting by its action on cycloxygenase.
54- b blocker has also alpha blockade action: labetalol.
55- iron absorption occurs mostly in duodenum.
56- iron required for : oxygen transport.
57- regular insulin: short acting, administered both s.c and i.v.
58- haloperidol differs from chlorpromazine in that haloperidol is not phenothiazine.
59- deferasirox(exjade®) antidote for iron overdose.
60- torsemide: ototoxicity, hypokalemia, C.I in patients sensitive to sulpha drugs.
61- IV anti-arrythmic ca channel blocker: verapamil.
62- Danazol: used for endometriosis.
63- Oxandrolone and stanazol are anabolic steroids.
64- Esmoperazole : decreases production of hydrochloric acid.
65- Beta carotene: precursor of vitamin A.
66-Simethicone: anti-flatulence.
67- Usual exp date for parenteral admixtures prepared in hospital pharmacy: 24 hours.
68-Route of injection limited to 1 ml or less: S.C
69- Osmotic pressure of 0.1 molar dextrose: 0.5 that of 0.1 molar NaCl.
70-Parenteral solutions isotonic with human RBCs have osmolality 300 mmol/L.
71- Heparin injected by: S.C or I.V infusion.
72- Insulin: not degraded only in liver(also in kidney) and available as non-prescription prep(in USA only).
73- Parenteral solution most stable in aq. Sol.: Gentamicin.
74- Pharmacy bulk packages: for prep of sterile products and no antimicrobial added.
75- Max. vol. allowed for bacteriostatic water for inj.: 30 ml.
76- Tuberculin: injected intradermally.
77- Immunoglubulin gamma injected: I.M.
78- Storage of biologicals: 2-8 C
79- Toxoids do not provide permanent immunity.
80- DPT vaccination for infants.
81- Viral infections: Influenza, mumps and measles.
82- Accidental drug poisoning: activated charcoal and ipecac syp.
83- Most recent biotechnology products available as : parenterals.
84- Monoclonal antibodies tech. used in: ovulation and pregnancy testing.
85- Calcium cont. antacids commonly cause: ???( forgot it)
86- Liposomes and nanoparticles are used for drug targeting.
87- Vaccines contraindicated in pregnancy : Measles , mumps and rubella( plz check it out)
88- Amoxapine : selective NE reuptake inhibitor.
89- Repaglinide: stimulates insulin secretion.
90- Tazobactam in Tazocin® : beta lactamase inhibitor.
91- T.B testing performed bef therapy with Infliximab.
92- Metformin: patients monitored for lactic acidosis.
93- Least suitable antibiotic before surgery: Cefazoline or cefuroxime
or clindamycin or tetracycline.( tetracycline but not sure)
94- Levofloxacin: fluoroquinolone antibiotic.
95- Acute asthmatic attacks: Pirbuterol.
96- Techniques for biotechnology products: gene splicing and monoclonal antibodies.
97- Passive immunity: anti-serum, active: toxoid, vaccine.
98- Erythromycin estolate: form most responsible for cholestatic jaundice.
99-Benzyl alcohol which is in bacteriostatic water not used in infants
تصحيح بعض الاسئله
4. and Amoxapine
9. Diacetylmorphine not Diacylmorphine
24. and Amrinone
32. and colesevelam
41. not dihydrotachysterol which is used in osteoporosis not hypothyroidism
85. Ca antacids cause flatulence
87.The 3 vaccines CI in pregnancy
B testing should be performed befor starting patient on:
a) gold b)amphotericin c) infliximab d)dutasteried
Defasirox is antidote for poisinig of
a)heavy metals b)benzodiazepines c)iron d)carbon monoxide
lactulose
decrease blood ammonia level
is alaxative
artificial sweetner
1only
3only
1and2
2and3
Which of the following morphine derivatives most cause dependance
ethylmorphine
hydrocodon
diacetylmorphine
methylmorphine
grapefruit juice should avoided with which
valasrtan
buspiron
felodipine
1only
2only
1and 2
2and 3
1,2,3
Colesevelam is classified as
HMG-COA reductase inhibitor
bile acid sequestrant
ACE inhibitor
which of the following decrease the production of HCL in stomach
olsalazine
mag hydroxide
esomperazole
1
3
1and 2
2and3
1,2,3
lactase enzyme for treatment of
cystic fibrosis
phenylketonuria
lactose intolerance
Which one is most useful in treatment infection caused by beta-lactmase producing staphylococci
cephalexine
alphaamoxicillin
cefuroxime
bacampicillin
Aspirin inhibit clotting by acting on
serotonine
xanthine oxidase
fibrinogen
cyclooxygenase
Which of them act as beta and alpha blocker
labetelol
sotalol
timolol
1
3
1and 2
2and 3
1,2,3
levofloxacin is classified as
fluroquinolone
aminoglycosid
macrolide
Danazole
anabolic steroid
estrogen
progesten
endometriosis treatment
drugs used in ttt of Alzahimer act on
dopaminergic
cholinergic
MAO
anticholinergic
used in ttt of inflammatory bowel disease
misoprostol
tegaserod
meslamine
metoclopromide
auranofin used in
Rh arthrities
multiple sclerosis
ulcerative colities
ear infection
Beta carotene is precursor of
betaseron
tocopherol
vit A
beta interferon
example of pure narcotic antagonist
buprenorphine
nalbuphine
naltrexone
used in ttt of thrombotic stroke
filgrastem
oprelvkin
ticlopidine
20-clozapine side effect
thrombocytopenia
***agranulocytosis
hypercalcemia
hypocalcemia
21-Morphine associated with which
1-pupillary constriction
2-constipation
3-respiratory depression
1only
2only
1and2
2and 3
***1,2,3
22-spironolacton most similar to
***eplerenon
hydrochlorothiazide
metolazon
bumetanide
23-haloperidol differ from chlorpromazinein that haloperidol
not taken parentral
not produce extrapyremidal effects
not a phenothiazine
1only
***3only
1and 2
2and 3
1,2,3
24-Repaglinide mech of action
stimulate the release of insuline
25-fosinopril classifed as
angiotensin antagonist
H2 blocker
**ACEIS
alpha blocker
26-Which of them classifed as antiseptics
propylhexedrine
chlohexidine gluconate
benzalkonim cloride
1only
3only
1,2
**2,3
1,2,3
27-Rasagline is
COMT inhibitor
anticholinergic
**MAO-B inhibitor
alpha agonist
Which of them MAO inhibitor -28-
gemcitabine
selegline
tranylcypromine
1only
3only
1,2
**2,3
1,2,3
29-In ttt of cardiac arrhythmia Sotalol similar to
tocainide
verapamil
**amiodaron
digoxin
30-Which of that true of irbesartan
not used during second and third trimester of pregnancy
indicated for ttt of diabetic nephropathy
it is an ACE inhibitor
1only
3only
**1,2
2,3
1,2,3
Moh 3-11-2010
1-carpidopa is dopa decarboxylase inhibitor
2- rasagiline: selective MAO-B
3-selegiline & tranylcipromine : MAO inhibitors
4- atomoxetine is selective NE reuptake inhibitor
5-cortcal stimulants: amphetamines,coccaine and pemoline
6-MORPHINE: pupil const,resp dep. and constipation
\7- METHADONE : controlled sub and analgesic
8- pure opioid antagonist: naltrexone
9-opioid with high dependance ability: diacylmorphine
10- SE of isotretinoin: conjunctivitis, pseudomotor cerebri and fetal abnormalities.
11-parenteral solutions isotonic with human rbcs have osmolality: 300
12-pharmacy bulk packages : For preparation of sterile parenterals and no antimicrobial included
13-max vol for bacteriostatic water4injection: 30 ml
14-alzeheimer due to defect in cholinergic transmission
15-dobutamine: B agonist and only parenteral
16-daltaparin : Prevention of stroke or coaggulation (not dissolveing)
17-method of administration of heparin: Iv and sc
18-least sedative anxiolytic: Buspirone
19-fat sol vitamin : Phytonadione
20-antioxidant: Ascorbic acid
21-fosinopril : Ace
22-irbesartan: Not used in 2nd and third trimester & used 4 diabetic nephropathy
23- dry mouth caused by ipratropium and montelukast(singulair]
24-milrinone: Positive inotropic
25- alopecia treated by minoxidil and finasteride
26- ticlopidine inhibits blood coaggulation.
27- grape fruit interferes with felodipine
28- auranofin used in rheumatoid arthritis
29- sotalol in anti arrythmic effect siimilar to amiodarone.
30- budesonide: Available as inhalation powder and oral mucosa should be rinsed after use.
(i am not sure of 22, 23 and 30)
31- If ICS and bronchodilator, the bronchodilator used first.
32- Colestipol : bile acid sequestrant.
33- Simvastatin: HMGCOA Reductase inh. And pregnancy category X.
34-Rosuvastatin: C.I. in: Active liver disease and myopathy.
35- Short acting hypnotic : Melatonin (not sure)
36 – Clozapine S.E.: agranulocytosis.
37- Rule of progestin component in combination contraceptive pills:
thickening of cervical mucosa making endometrial lining irreceptive for
fertilized ovum.
38 – Tinea: TTT: terbinafine and nystatin.
39- Famotidine interferes with histamine receptors.
40- Betamethasone: most potent systemic cortisone.
41- hypothyroidism treated by : dihydrotachysterol.
42- acute gout treated by : naproxen.
43- b lactamase producing staph. Treated by bacampicillin(not sure).
44- Sulfonamides antagonized by : PABA.
45- chlorohexidine and benzalkonium are antiseptics.
46- permethrin: only used topically.
47- rizatriptan and methysergide for ttt of migraine.
the answer in APPLETON LANGE was both.
48- lactase enz used in : lactose intolerance.
49- endorphins: endogenous peptides.
50 disadv. Of cimetidine : inh of hepatic enzymes.
51-lactulose: laxative and decreases ammonia levels.
52-mesalamina(asacol®) used for IBD
53- aspirin inhibits clotting by its action on cycloxygenase.
54- b blocker has also alpha blockade action: labetalol.
55- iron absorption occurs mostly in duodenum.
56- iron required for : oxygen transport.
57- regular insulin: short acting, administered both s.c and i.v.
58- haloperidol differs from chlorpromazine in that haloperidol is not phenothiazine.
59- deferasirox(exjade®) antidote for iron overdose.
60- torsemide: ototoxicity, hypokalemia, C.I in patients sensitive to sulpha drugs.
61- IV anti-arrythmic ca channel blocker: verapamil.
62- Danazol: used for endometriosis.
63- Oxandrolone and stanazol are anabolic steroids.
64- Esmoperazole : decreases production of hydrochloric acid.
65- Beta carotene: precursor of vitamin A.
66-Simethicone: anti-flatulence.
67- Usual exp date for parenteral admixtures prepared in hospital pharmacy: 24 hours.
68-Route of injection limited to 1 ml or less: S.C
69- Osmotic pressure of 0.1 molar dextrose: 0.5 that of 0.1 molar NaCl.
70-Parenteral solutions isotonic with human RBCs have osmolality 300 mmol/L.
71- Heparin injected by: S.C or I.V infusion.
72- Insulin: not degraded only in liver(also in kidney) and available as non-prescription prep(in USA only).
73- Parenteral solution most stable in aq. Sol.: Gentamicin.
74- Pharmacy bulk packages: for prep of sterile products and no antimicrobial added.
75- Max. vol. allowed for bacteriostatic water for inj.: 30 ml.
76- Tuberculin: injected intradermally.
77- Immunoglubulin gamma injected: I.M.
78- Storage of biologicals: 2-8 C
79- Toxoids do not provide permanent immunity.
80- DPT vaccination for infants.
81- Viral infections: Influenza, mumps and measles.
82- Accidental drug poisoning: activated charcoal and ipecac syp.
83- Most recent biotechnology products available as : parenterals.
84- Monoclonal antibodies tech. used in: ovulation and pregnancy testing.
85- Calcium cont. antacids commonly cause: ???( forgot it)
86- Liposomes and nanoparticles are used for drug targeting.
87- Vaccines contraindicated in pregnancy : Measles , mumps and rubella( plz check it out)
88- Amoxapine : selective NE reuptake inhibitor.
89- Repaglinide: stimulates insulin secretion.
90- Tazobactam in Tazocin® : beta lactamase inhibitor.
91- T.B testing performed bef therapy with Infliximab.
92- Metformin: patients monitored for lactic acidosis.
93- Least suitable antibiotic before surgery: Cefazoline or cefuroxime
or clindamycin or tetracycline.( tetracycline but not sure)
94- Levofloxacin: fluoroquinolone antibiotic.
95- Acute asthmatic attacks: Pirbuterol.
96- Techniques for biotechnology products: gene splicing and monoclonal antibodies.
97- Passive immunity: anti-serum, active: toxoid, vaccine.
98- Erythromycin estolate: form most responsible for cholestatic jaundice.
99-Benzyl alcohol which is in bacteriostatic water not used in infants
تصحيح بعض الاسئله
4. and Amoxapine
9. Diacetylmorphine not Diacylmorphine
24. and Amrinone
32. and colesevelam
41. not dihydrotachysterol which is used in osteoporosis not hypothyroidism
85. Ca antacids cause flatulence
87.The 3 vaccines CI in pregnancy
B testing should be performed befor starting patient on:
a) gold b)amphotericin c) infliximab d)dutasteried
Defasirox is antidote for poisinig of
a)heavy metals b)benzodiazepines c)iron d)carbon monoxide
lactulose
decrease blood ammonia level
is alaxative
artificial sweetner
1only
3only
1and2
2and3
Which of the following morphine derivatives most cause dependance
ethylmorphine
hydrocodon
diacetylmorphine
methylmorphine
grapefruit juice should avoided with which
valasrtan
buspiron
felodipine
1only
2only
1and 2
2and 3
1,2,3
Colesevelam is classified as
HMG-COA reductase inhibitor
bile acid sequestrant
ACE inhibitor
which of the following decrease the production of HCL in stomach
olsalazine
mag hydroxide
esomperazole
1
3
1and 2
2and3
1,2,3
lactase enzyme for treatment of
cystic fibrosis
phenylketonuria
lactose intolerance
Which one is most useful in treatment infection caused by beta-lactmase producing staphylococci
cephalexine
alphaamoxicillin
cefuroxime
bacampicillin
Aspirin inhibit clotting by acting on
serotonine
xanthine oxidase
fibrinogen
cyclooxygenase
Which of them act as beta and alpha blocker
labetelol
sotalol
timolol
1
3
1and 2
2and 3
1,2,3
levofloxacin is classified as
fluroquinolone
aminoglycosid
macrolide
Danazole
anabolic steroid
estrogen
progesten
endometriosis treatment
drugs used in ttt of Alzahimer act on
dopaminergic
cholinergic
MAO
anticholinergic
used in ttt of inflammatory bowel disease
misoprostol
tegaserod
meslamine
metoclopromide
auranofin used in
Rh arthrities
multiple sclerosis
ulcerative colities
ear infection
Beta carotene is precursor of
betaseron
tocopherol
vit A
beta interferon
example of pure narcotic antagonist
buprenorphine
nalbuphine
naltrexone
used in ttt of thrombotic stroke
filgrastem
oprelvkin
ticlopidine
20-clozapine side effect
thrombocytopenia
***agranulocytosis
hypercalcemia
hypocalcemia
21-Morphine associated with which
1-pupillary constriction
2-constipation
3-respiratory depression
1only
2only
1and2
2and 3
***1,2,3
22-spironolacton most similar to
***eplerenon
hydrochlorothiazide
metolazon
bumetanide
23-haloperidol differ from chlorpromazinein that haloperidol
not taken parentral
not produce extrapyremidal effects
not a phenothiazine
1only
***3only
1and 2
2and 3
1,2,3
24-Repaglinide mech of action
stimulate the release of insuline
25-fosinopril classifed as
angiotensin antagonist
H2 blocker
**ACEIS
alpha blocker
26-Which of them classifed as antiseptics
propylhexedrine
chlohexidine gluconate
benzalkonim cloride
1only
3only
1,2
**2,3
1,2,3
27-Rasagline is
COMT inhibitor
anticholinergic
**MAO-B inhibitor
alpha agonist
Which of them MAO inhibitor -28-
gemcitabine
selegline
tranylcypromine
1only
3only
1,2
**2,3
1,2,3
29-In ttt of cardiac arrhythmia Sotalol similar to
tocainide
verapamil
**amiodaron
digoxin
30-Which of that true of irbesartan
not used during second and third trimester of pregnancy
indicated for ttt of diabetic nephropathy
it is an ACE inhibitor
1only
3only
**1,2
2,3
1,2,3
