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    محاضرة د.هاني قناوي Streptococcus Spp

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    محاضرة د.هاني قناوي Streptococcus Spp Empty محاضرة د.هاني قناوي Streptococcus Spp

    مُساهمة من طرف admin السبت يناير 01, 2011 12:04 pm

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    Streptococcus
    From Wikipedia, the free encyclopedia
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    Not to be confused with Staphylococcus.
    Streptococcus
    Scientific classification
    Kingdom: Bacteria
    Phylum: Firmicutes
    Class: Bacilli[1]
    Order: Lactobacillales
    Family: Streptococcaceae
    Genus: Streptococcus
    Rosenbach, 1884
    Species

    S. agalactiae
    S. anginosus
    S. bovis
    S. canis
    S. constellatus
    S. dysgalactiae
    S. equi
    S. equinus
    S. iniae
    S. intermedius
    S. mitis
    S. mutans
    S. oralis
    S. parasanguinis
    S. peroris
    S. pneumoniae
    S. pyogenes
    S. ratti
    S. salivarius
    S. salivarius ssp. thermophilus
    S. sanguinis
    S. sobrinus
    S. suis
    S. uberis
    S. vestibularis
    S. viridans
    S. zooepidemicus

    Streptococcus is a genus of spherical Gram-positive bacteria belonging to the phylum Firmicutes[2] and the lactic acid bacteria group. Cellular division occurs along a single axis in these bacteria, and thus they grow in chains or pairs, hence the name — from Greek στρεπτος streptos, meaning easily bent or twisted, like a chain (twisted chain). Contrast this with staphylococci, which divide along multiple axes and generate grape-like clusters of cells. Streptococci are oxidase- and catalase-negative, and many are facultative anaerobes.

    In 1984, many organisms formerly considered Streptococcus were separated out into the genera Enterococcus and Lactococcus.[3]
    Contents
    [hide]

    * 1 Pathogenesis
    o 1.1 Alpha-hemolytic
    + 1.1.1 Pneumococci
    + 1.1.2 The Viridans group: alpha hemolytic
    o 1.2 Beta-hemolytic
    + 1.2.1 Group A
    + 1.2.2 Group B
    + 1.2.3 Group C
    + 1.2.4 Group G streptococci
    o 1.3 Non-hemolytic
    + 1.3.1 Group D (enterococci)
    * 2 Treatment
    * 3 See also
    * 4 References
    * 5 External links

    [edit] Pathogenesis
    Streptococcal classification.

    In addition to streptococcal pharyngitis (or strep throat), certain Streptococcus species are responsible for many cases of meningitis, bacterial pneumonia, endocarditis, erysipelas and necrotizing fasciitis (the 'flesh-eating' bacterial infections). However, many streptococcal species are non-pathogenic. Indeed, Streptococci are a necessary ingredient in Emmentaler ("Swiss") cheese. Streptococci are also part of the normal commensal flora of the mouth, skin, intestine, and upper respiratory tract of humans.

    As a rule, individual species of Streptococcus are classified based on their hemolytic properties.[4] Alpha hemolysis is caused by an oxidation of iron in hemoglobin, giving it a greenish color on blood agar. Beta-hemolysis is complete rupture of red blood cells, giving distinct, wide, clear areas around bacterial colonies on blood agar. Other streptococci are labeled as gamma hemolytic, actually a misnomer, as no hemolysis takes place.

    Beta-hemolytic streptococci are further characterised via the Lancefield serotyping – based on specific carbohydrates in the bacterial cell wall.[5] These are named Lancefield groups A to v (except I and J). In the medical setting, the most important groups are the alpha-hemolytic streptococci, S. pneumoniae and Streptococcus Viridans-group, and the beta-hemolytic streptococci of Lancefield groups A and B (also known as “Group A strep” and “Group B strep”).
    [edit] Alpha-hemolytic
    [edit] Pneumococci

    * S. pneumoniae, a leading cause of bacterial pneumonia and occasional etiology of otitis media, sinusitis, meningitis and peritonitis.

    [edit] The Viridans group: alpha hemolytic

    * S. mutans, a contributor to dental caries
    * S. mitis, mostly found around cheek region
    * S. sanguinis, no preference of locations
    * S. salivarius, mostly found on the dorsal side of the tongue
    * S. salivarius ssp. thermophilus, used in the manufacture of some cheeses and yogurts
    * S. constellatus, occasional human pathogen, notable as colonies grown on blood agar smell strongly of caramel

    [edit] Beta-hemolytic
    Alpha (left) and Beta (right) hemolytic streptococci grown on blood agar
    [edit] Group A

    S. pyogenes, also known as Group A Streptococcus (GAS), is the causative agent in Group A streptococcal infections, including streptococcal pharyngitis ("strep throat" AmE), acute rheumatic fever, scarlet fever, acute glomerulonephritis and necrotizing fasciitis. If strep throat is not treated, it can develop into rheumatic fever, a disease that affects the joints and heart valves. Other Streptococcus species may also possess the Group A antigen, but human infections by non-S. pyogenes GAS strains (some S. dysgalactiae subsp. equisimilis and S. anginosus Group strains) appear to be uncommon.

    Group A Streptococcus infection is generally diagnosed with a Rapid Strep Test (AmE) or by culture.
    [edit] Group B

    S. agalactiae, or GBS, causes pneumonia and meningitis in neonates and the elderly, with occasional systemic bacteremia. They can also colonize the intestines and the female reproductive tract, increasing the risk for premature rupture of membranes and transmission to the infant. The American College of Obstetricians and Gynecologists, American Academy of Pediatrics and the Centers for Disease Control recommend all pregnant women between 35 and 37 weeks gestation should be tested for GBS. Women who test positive should be given prophylactic antibiotics during labor, which will usually prevent transmission to the infant.[6] In the UK, clinicians have been slow to implement the same standards as the US, Australia and Canada. In the UK, only 1% of maternity units test for the presence of Group B Streptococcus.[7] Although The Royal College of Obstetricians and Gynaecologists issued risk-based guidelines in 2003 (due for review 2006), the implementation of these guidelines has been patchy. Some groups feel that as a result over 75 infants in the UK die each year of GBS related disease and another 600 or so suffer serious infection, most of which could be prevented [8] however this is yet to be substantiated by randomized controlled trial in the UK setting and, given the evidence for the efficacy of testing and treating from other countries, it may be that the large-scale trial necessary would receive neither funding nor ethics approval.[9]
    [edit] Group C

    Includes S. equi, which causes strangles in horses,[10] and S. zooepidemicus - S. equi is a clonal descendent or biovar of the ancestral S. zooepidemicus - which causes infections in several species of mammals including cattle and horses.

    The Group D strains include Streptococcus bovis and Streptococcus equinus.
    [edit] Group G streptococci

    These streptococci are usually but not exclusively beta hemolytic. Streptococcus canis is an example of a GGS which is typically found on animals but can cause infection in humans.
    [edit] Non-hemolytic
    [edit] Group D (enterococci)

    Many former Group D streptococci have been reclassified and placed in the genus Enterococcus (including S. faecalis, S. faecium, S. durans, and S. avium).[11] For example, Streptococcus faecalis is now Enterococcus faecalis.

    The remaining non-enterococcal Group D strains include Streptococcus bovis and Streptococcus equinus.

    Non-hemolytic streptococci rarely cause illness. However, weakly hemolytic group D beta-hemolytic streptococci and Listeria monocytogenes (which is actually a gram positive bacillus) should not be confused with non-hemolytic streptococci.
    [edit] Treatment

    * See List of antibiotics.

    [edit] See also

    * Streptokinase

    [edit] References

    1. ^ "Result of detail taxonomy information". TXSearch Taxonomy Retrieval. DNA Data Bank of Japan. 19 February 2010. [ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط] Retrieved 30 March 2010.
    2. ^ Ryan KJ, Ray CG, ed (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. ISBN 0-8385-8529-9.
    3. ^ Facklam R (October 2002). "What happened to the streptococci: overview of taxonomic and nomenclature changes". Clin. Microbiol. Rev. 15 (4): 613–30. doi:10.1128/CMR.15.4.613-630.2002. PMID 12364372. PMC 126867. [ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط]
    4. ^ Patterson MJ (1996). Streptococcus. In: Baron's Medical Microbiology (Baron S et al., eds.) (4th ed.). Univ of Texas Medical Branch. (via NCBI Bookshelf) ISBN 0-9631172-1-1.
    5. ^ Facklam R (2002). "What happened to the streptococci: overview of taxonomic and nomenclature changes". Clin Microbiol Rev 15 (4): 613–30. doi:10.1128/CMR.15.4.613-630.2002. PMID 12364372.
    6. ^ Schrag S, Gorwitz R, Fultz-Butts K, Schuchat A (2002). "Prevention of perinatal group B streptococcal disease. Revised guidelines from CDC". MMWR Recomm Rep 51 (RR-11): 1–22. PMID 12211284.
    7. ^ Hughes, RG, et al.. Prevention of Early Onset Neonatal Group B Streptococcal Disease. Royal College of Obstetricians and Gynaecologists. [ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط]
    8. ^ "Group B Strep Support Home Page". Group B Strep Support. 2007-01-09. [ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط]
    9. ^ "RCOG: Preventing group B streptococcus infection in new born babies". RCOG. 2006-02. [ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط]
    10. ^ Harrington D, Sutcliffe I, Chanter N (2002). "The molecular basis of Streptococcus equi infection and disease". Microbes Infect 4 (4): 501–10. doi:10.1016/S1286-4579(02)01565-4. PMID 11932201.
    11. ^ Ruoff KL (1990). "Recent taxonomic changes in the genus Enterococcus". Eur J Clin Microbiol Infect Dis 9 (2): 75–9. doi:10.1007/BF01963630. PMID 2108030.

    [edit] External links

    * Streptococcus genomes and related information at PATRIC, a Bioinformatics Resource Center funded by NIAID
    * Prevention of Perinatal Group B Streptococcal Disease August 16, 2002 MMWR 2000;49:228-232.
    * The Canadian Strep B Foundation
    * The UK Group B Strep Support charity

    [show]
    v • d • e
    Prokaryotes: Bacteria classification
    Domain: Archaea – Bacteria – Eukaryota
    G-/
    OM
    Terra-/Glidobacteria (BV1)

    Eobacteria (Chloroflexi, Deinococcus-Thermus) · Cyanobacteria · Thermodesulfobacteria · thermophiles (Aquificae · Thermotogae)
    Proteobacteria (BV2)

    Alpha · Beta · Gamma (Enterobacteriaceae) · Delta · Epsilon
    BV4

    Spirochaetes

    Spirochaetes
    Sphingobacteria

    Fibrobacteres · Chlorobi/Bacteroidetes
    Planctobacteria

    Chlamydiae/Verrucomicrobia · Planctomycetes
    Other GN

    Acidobacteria · Chrysiogenetes · Deferribacteres · Fusobacteria · Gemmatimonadetes · Nitrospirae · Synergistetes · Dictyoglomi · Lentisphaerae
    G+/
    no OM
    Firmicutes
    (BV3)

    Bacilli


    Bacillales: Bacillaceae · Listeriaceae · Staphylococcaceae
    Lactobacillales: Enterococcaceae · Lactobacillaceae · Leuconostocaceae · Streptococcaceae
    Clostridia

    Clostridiales · Halanaerobiales · Thermoanaerobacterales
    Tenericutes/
    Mollicutes

    Mycoplasmatales · Entomoplasmatales · Anaeroplasmatales · Acholeplasmatales · Haloplasmatales
    Actinobacteria
    (BV5)

    Actinobacteridae

    Actinomycetales


    Actinomycineae: Actinomycetaceae

    Corynebacterineae: Mycobacteriaceae · Nocardiaceae · Corynebacteriaceae

    Frankineae: Frankiaceae
    Micrococcineae: Brevibacteriaceae
    Bifidobacteriales

    Bifidobacteriaceae
    Other subclasses

    Acidimicrobidae · Coriobacteridae · Rubrobacteridae · Sphaerobacteridae

    M: BAC


    bact (clas)


    gr+f/gr+a(t)/gr-p(c)/gr-o


    drug(J1p, w, n, m, vacc)
    [show]
    v • d • e
    Firmicutes (low-G+C) Infectious diseases · Bacterial diseases: G+ (primarily A00–A79, 001–041, 080–109)
    Bacilli
    Lactobacillales
    (Cat-)

    Streptococcus

    α

    optochin susceptible: S. pneumoniae (Pneumococcal infection)
    optochin resistant: S. viridans (S. mitis, S. mutans, S. oralis, S. sanguinis, S. sobrinus, milleri group)
    β

    A, bacitracin susceptible: S. pyogenes (Scarlet fever, Erysipelas, Rheumatic fever, Streptococcal pharyngitis)
    B, bacitracin resistant, CAMP test+: S. agalactiae
    γ

    D, BEA+: Streptococcus bovis
    Enterococcus

    BEA+: Enterococcus faecalis (Urinary tract infection) · Enterococcus faecium
    Bacillales
    (Cat+)

    Staphylococcus

    Cg+ S. aureus (Staphylococcal scalded skin syndrome, Toxic shock syndrome, MRSA)
    Cg- novobiocin susceptible (S. epidermidis) · novobiocin resistant (S. saprophyticus)
    Bacillus

    Bacillus anthracis (Anthrax) · Bacillus cereus (Food poisoning)
    Listeria

    Listeria monocytogenes (Listeriosis)
    Clostridia
    Clostridium (spore-forming)

    motile: Clostridium difficile (Pseudomembranous colitis) · Clostridium botulinum (Botulism) · Clostridium tetani (Tetanus)
    nonmotile: Clostridium perfringens (Gas gangrene, Clostridial necrotizing enteritis)
    Peptostreptococcus (non-spore forming)

    Peptostreptococcus magnus
    Mollicutes
    Mycoplasmataceae

    Ureaplasma urealyticum (Ureaplasma infection) · Mycoplasma genitalium · Mycoplasma pneumoniae (Mycoplasma pneumonia)
    Anaeroplasmatales

    Erysipelothrix rhusiopathiae (Erysipeloid)

    M: BAC


    bact (clas)


    gr+f/gr+a(t)/gr-p(c)/gr-o


    drug(J1p, w, n, m, vacc)
    Retrieved from "http://en.wikipedia.org/wiki/Streptococcus"
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